Effect of fluoride gels on remineralization of artificial caries

Methods: Subjects (n=4) were randomly allocated one of the fluoride gels, which was applied to the test half-slabs. Each subject wore the appliance at least 12 hours daily for 15 days, with a 7-day washout period between crossovers. After each 15-day cycle, test and control half-slabs were paired, embedded in resin, sectioned, and subjected to analysis under polarized light microscope and quantified with an Image-Pro plus. All data were subjected to statistical analyses at 0.05 significance level.

Results: The mean lesion areas of CU gel and Pascal were 134,158.3 and 135,599.6 µm² compared with the mean lesion areas of control groups 165,374.5 and 178,624.6 µm², respectively. Both fluoride gels significantly reduced incipient artificial lesions compared to controlled sections (paired t-test, p<.05). However, there was no statistical difference between CU gel and Pascal (p>.05).

Conclusion: Both fluoride gels were effective in inhibiting new caries lesions in situ.