Characteristics of VSCs in oral cavity in H.pylori positive subjects

Objectives: Many studies had indicated that H.pylori infection in stomach may have some relationship with oral malodor. The aim of this study was to evaluate the characteristics of VSCs in oral cavity in H.pylori positive subjects. Methods: Thirty-five periodontally healthy subjects without systemic diseases were enrolled into the study. The H.pylori infection in stomach was identified by ¹⁴C Urea Breath Test (UBT). The concentrations of three volatile sulfur compounds were evaluated by a portable gas chromatoghraphy (OralChroma^TM). Student t Test and Mann-Whiney U Test were used to analyze the data. Results: The concentration and proportion of dimethyl sulfide were significantly higher in H.pylori positive subjects than that in H.pylori negative ones (P<0.05). There were no statistical differences in the values of hydrogen sulfide and methyl mercaptan in H.pylori positive and negative ones. Conclusions: It was indicated that concentration and proportion of dimethyl sulfide were statistically higher in H.pylori positive subjects than that in negative ones.H.pylori infection in stomach may cause halitosis and dimethyl sulfide may be one reason for that.