IADR Abstract Archives
Efficacy of Silver Diamine Fluoride on Caries Arrestment in Primary Teeth
Objectives: The aim of the present study was to systematically review the literature to answer the question: is Silver Diamine Fluoride (SDF) effective in arresting caries in primary teeth ?
Methods: Electronic databases including Medline (via Pubmed), the Cochrane Library (Central), Scopus, EBSCO and scienceDirect database, without restrictions on publication year or publication language, were searched.
The initial search was conducted on May 2019 and a subsequent search was performed on August 2020. Additional studies were sought through hand searching of pediatric dentistry journals.
Only randomized clinical trials published after 2010 comparing the caries-arresting effect of SDF treatment with other active treatment or placebo in primary teeth were selected.
In order to assess the quality of the methodology and the results outcomes of the included articles, a modified version of the Consolidated Standards of Reporting Trials (CONSORT) 2010 checklist for clinical trials quality assessment was used.
Results: Out of 266 articles identified in initial research, 8 papers meeting the inclusion criteria remained in the review. The mean age of the patients in the included studies was 2-5 years. The most common used SDF concentration was 38%.
SDF applications were compared with NaF, atraumatic restorative treatment (ART), resin infiltration, glass ionomer, and placebo.
Yearly application of SDF was reported in six studies, three weekly interval applications was reported in three studies and semi-annual application in two studies.
The average proportion of arrested caries lesions in SDF group was higher than the placebo groups. Three studies reported that applications of SDF solution was more effective in arresting dentine caries than the applications of NaF varnish. Four studies showed that SDF have similar results as ART, AgNO3, and resin sealant in arresting caries lesions. And two studies reported that SDF was less aesthetic than glass ionomer and ART.
Conclusions: The systematic review showed that SDF can be more effective than other active treatments in arresting dental caries in primary teeth, but there was no consensus regarding the number and frequency of applications of SDF use to arrest caries.
Methods: Electronic databases including Medline (via Pubmed), the Cochrane Library (Central), Scopus, EBSCO and scienceDirect database, without restrictions on publication year or publication language, were searched.
The initial search was conducted on May 2019 and a subsequent search was performed on August 2020. Additional studies were sought through hand searching of pediatric dentistry journals.
Only randomized clinical trials published after 2010 comparing the caries-arresting effect of SDF treatment with other active treatment or placebo in primary teeth were selected.
In order to assess the quality of the methodology and the results outcomes of the included articles, a modified version of the Consolidated Standards of Reporting Trials (CONSORT) 2010 checklist for clinical trials quality assessment was used.
Results: Out of 266 articles identified in initial research, 8 papers meeting the inclusion criteria remained in the review. The mean age of the patients in the included studies was 2-5 years. The most common used SDF concentration was 38%.
SDF applications were compared with NaF, atraumatic restorative treatment (ART), resin infiltration, glass ionomer, and placebo.
Yearly application of SDF was reported in six studies, three weekly interval applications was reported in three studies and semi-annual application in two studies.
The average proportion of arrested caries lesions in SDF group was higher than the placebo groups. Three studies reported that applications of SDF solution was more effective in arresting dentine caries than the applications of NaF varnish. Four studies showed that SDF have similar results as ART, AgNO3, and resin sealant in arresting caries lesions. And two studies reported that SDF was less aesthetic than glass ionomer and ART.
Conclusions: The systematic review showed that SDF can be more effective than other active treatments in arresting dental caries in primary teeth, but there was no consensus regarding the number and frequency of applications of SDF use to arrest caries.