Efficacy of Calcium Phosphate Compound on Remineralization of White Lesions

Objectives: To compare the efficacy of casein phosphopeptide - amorphous calcium phosphate (CPP-ACP), calcium sodium - phosphosilicate (CPS) and fluoride gel on remineralization of artificial enamel white lesions. Methods: The labial surface of each tooth, from 12 bovine incisors, was cut into 2 pieces; control and experimental. After that, artificial white lesions were created by immersing all samples into demineralizing solution. The color of white lesions was measured by the spectrophotometer (Hunter lab Ultrascan XE) before treatment as baseline. Then, CPP-ACP, CPS or fluoride gel was applied on the white lesions according to the manufacturer instructions. After treatment, color measurement was done weekly for 5 weeks and samples were photographed at the end of experiment. Results: There is a clear improvement in color of white lesions from all 3 treatment groups comparing to control groups at 5 weeks. However, there was no difference between the 3 treatment groups. Conclusions: CPP-ACP, CPS and fluoride gel are effective in reversing the appearance of white lesions on bovine enamel and the efficacy of three treatments is not different.