Pocket Depth on Menopausal Women not Correlated With Estrogen Receptor

Introduction:In women, hormonal changes troughout life period has influence to periodontium health. Estrogen deficiency during menopause had been considered with increasing alveolar bone loss and periodontium loss attachment which can increase severity of periodontal disease. Objectives:The aim of this study is to detect estrogen receptor alpha and beta on periodontal pocket of menopausal women and to determinate correlation between immunoexpression of estrogen receptor alpha and beta with the severity of periodontitis which determinate based on periodontal pocket depth in order to explore the role of estrogen in the pathogenesis of periodontitis on menopausal women Material and Methods:This study is Cross-sectional Observation. The sample was obtained from scrapping periodontal pocket wall on menopausal women and reproductive women that included to criteria that determinated previously. We measured clinical status of periodontium include gingiva, bleeding on probing and periodontal pocket depth. The scrapping periodontal pocket smeared on object glass, fixed with alcohol 95% and then stained with estrogen receptor alpha and beta antibody. Result:13 menopausal women aged 58,8 ± 6,06 years old, duration of menopause was 5,6 ± 4,3 years and 11 reproductive women aged 39,9 ± 7,04 years old was consisted in this study. The average of periodontal pocket depth in menopausal women was 4,62 ± 1,09 mm and 4,27 ± 1,01 in reproductive women. Immunoexpression of estrogen receptor alpha and beta is 27,16% and 14,72% on menopausal women and 32,11% and 13,51% on reproductive women respectively. There is no correlation between immunoexpression of estrogen receptor alpha and beta with periodontal pocket depth both on menopausal women and reproductive women. Conclusion:The severity of periodontitis on menopausal women which determinate based on periodontal pocket depth is not correlated with immunoexpression of estrogen receptor sugessted that estrogen do not have play a valuable role in the periodontal pocket formation.