The Effect of Continuous and Interrupted Forces on Interleukin-1ß Level

Continuous force moves tooth faster than interrupted force, but no information about the activity of resorption process causing by both of the forces. As research of IL-1ß approaches, more information about how the periodontal ligament gives reaction to mechanic force can be achieved, because with IL-1ß as the inflammatory mediator, the osteoclast will be activated on bone resorption process. Objectives: to evaluate the effect of continuous and interrupted force on IL-1ß level in gingival crevicular fluid of distal canines on canines retraction. And whether duration of continuous and interrupted force influence the IL-1ß level in gingival crevicular fluid of distal canines on canines retraction. Methods: clinical experiment parallel design study used closed NiTi coil spring (continuous force) and closed power chain (interrupted force) to retract upper canines. Gingival crevicular fluid was collected by using a 2 mm x 8 mm Whatmann 3 MM filter paper before activation, and the following time periods : 1 hour, 24 hours, 168 hours, and 504 hours. The IL-1ß levels were analysed by ELISA method. Results: using two-way ANOVA showed there was no significant difference (F=0,260; p=0,615) between continuous and interrupted orthodontic forces on the IL-1ß levels in gingival crevicular fluid, but there was significantly different (F=3,72; p=0,005) between both groups according the duration of force application. The difference detected only between 1 hour time period of continuous force and 504 hours time period of interrupted force application. Conclusion: there was no difference of IL-1ß level in gingival crevicular fluid of distal canines either using continuous or interrupted force on upper canine retraction.