Effects of Dentifrices on Artificial Caries-like Lesions: a pH-cycling Study

Objective: To evaluate remineralizing effects of three dentifrices, Vicco® by Vicco Labs, India, Perioe Cavity Care® by LG Care, Korea and Colgate Total® by Colgate-Palmolive, Thailand on artificial caries-like lesions. Methods: Extracted third molars were painted with nail varnish, leaving 1mm wide window before placing in demineralizing solution for 96h to produce artificial carious lesions 150-200ìm deep. Teeth were then cut longitudinally into 100-150µm thick sections and randomly assigned to three groups (n=9). Polarized light microscope and microradiography was used to evaluate lesion depth, before and after in vitro 10 day pH cycle. Sections in Group A were treated with Vicco® by Vicco Labs, India (-ve control), Group B were treated with Perioe Cavity Care® by LG Care, Korea and Group C were treated with Colgate Total® by Colgate-Palmolive, Thailand. Results: Mean lesion depths in Groups B and C reduced by 7% and 12% respectively, whereas lesion depth increased by 13% in Group A. Comparisons made among groups using ANOVA and Student-Newman-Keuls tests showed that three groups were significantly different from each other (p<0.05). Conclusions: Perioe Cavity Care® and Colgate Total® remineralized initial carious lesions. However, remineralizing potential of Colgate Total® was shown to be higher than that of Perioe Cavity Care®.