Nowadays, facial esthetics is much more concerned in modern orthodontics. Patient's profile appearance is one of the essential diagnostic criteria for orthodontic planning and treatment. Objectives: The aims of this study were to determine the facial profile preferences of various panels judging treated Class II division 1 patients and to evaluate the differences in the attitude toward the facial improvement among different groups of panels. Methods: Random pre- and post-treatment (or post- and pre-) line-drawing profiles of 195 patients were presented to 30 orthodontists, 30 other dentists, 40 young and 40 adult laypersons to evaluate the improvement of the patients' profile esthetics. The patients were evaluated separately by sex dimorphism and the skeletal pattern: Class I, mild Class II, and marked Class II. Visual analogue scale was used to determine the intensity of each judge's preference. Median scores of each group of panels were compared by using Friedman 2-way ANOVA to evaluate the differences in the panels' attitude toward the profile improvement of individual patients. Using the results of all panels' perceptions, the patients were categorized into 3 subgroups; better profile, little changed profile, and worse profile. Results: There were significant differences in the attitudes among panels' groups except for the young and adult laypersons (p<0.01). Orthodontists tended to be more sensitive in detecting the improvement of treated profiles than other panels (mean rank=2.92). While other dentists viewed the improved profiles differently from orthodontists and laypersons (mean rank=1.83). Conclusions: There were the differences in facial profile perception among the orthodontists and other panels. It is important in orthodontic treatment planning to ascertain what the patients expect for mutual understanding and preparing their expectations. This study was supported by a grant from the Faculty of Graduate Studies, Mahidol University and Ministry of University Affair.