Objective: The purpose of this study was to evaluate the effect of four primers, i.e., METAFAST (MF), Cesead II Opaque Primer (CP II), METAL PRIMER II (MP II), and ALLOY PRIMER (AP), on the shear bond strength between two resin cements, Panavia F (PF) and Superbond C&B (SB), on Nickel-Chromium alloy. Methods: Casting alloys cylinders (f7x2, f9x2mm, 100 pairs, n=10 in each group) were used. They were cemented with each of two resin cements with and without primer. Then they were stored in a 37±2°C water bath for 24 hrs and subjected to shear bond test using universal testing machine. One-way ANOVA was use to analyse. Results: The group using PF with CP II showed the highest mean shear bond strength and demonstrated a significant difference compared to those without primer. There was no significant difference in the ones using SB with or without primer. Conclusion: This study showed the use of adhesive primer for bonding between Nickel-Chromium alloy and Panavia F resulted in a high and durable bond strength.