IADR Abstract Archives
Preventive Effect of Silver Diamine Fluoride on Dentine Erosion
Objectives: To investigate the preventive effect of 38% silver diamine fluoride (SDF) on dental erosion in dentine blocks with salivary pellicle
Methods: 105 dentine blocks were allocated into three groups. Group 1 received a one-off 38% SDF, Group 2 received stannous chloride-containing fluoride (SnCl2/AmF/NaF) daily and Group 3 received deionized water daily. The blocks were immersed in fresh saliva before each erosive challenge and surface treatment to form salivary pellicle. The morphology of the salivary pellicles was assessed by atomic force microscopy (AFM). The treated blocks were subjected to a 5-time 120s/day citric acid at pH 3.2 for 14 days. Dentine microhardness loss, dentine surface loss, crystal characteristics and surface morphologies were assessed using microhardness test, non-contact profilometry, X-ray diffraction (XRD) and scanning electron microscopy (SEM), respectively. Data of dentine hardness loss and dentine surface loss were analysed by one-way ANOVA and Tukey’s multiple comparison post hoc test.
Results: AFM revealed salivary protein clumped on dentine block surface in Groups 1 and 2. Dentine microhardness loss (±SD in %) in Groups 1 to 3 were 15.20 ± 2.18, 17.42 ± 2.10, and 28.17 ± 2.20, respectively (Groups 1=2<3; p<0.001). The dentine surface loss (±SD in μm) in Groups 1 to 3 were 4.75 ± 0.28, 4.62 ± 0.33, and 9.66 ± 0.32, respectively (Groups 1=2<3; p<0.001). XRD analysis showed silver chloride, silver phosphate and silver fluoride formed in Group 1, ammonium fluoride, sodium fluoride and calcium fluoride formed in Group 2, while only hydroxyapatite were detected in Group 3. SEM revealed dentinal tubular occlusion in Groups 1-2 and exposed dentinal tubules in Group 3.
Conclusions: A one-off application of 38% SDF with salivary pellicle had promising results initial outcome similar to stannous chloride-containing fluoride in preventing human dentine erosion.
Methods: 105 dentine blocks were allocated into three groups. Group 1 received a one-off 38% SDF, Group 2 received stannous chloride-containing fluoride (SnCl2/AmF/NaF) daily and Group 3 received deionized water daily. The blocks were immersed in fresh saliva before each erosive challenge and surface treatment to form salivary pellicle. The morphology of the salivary pellicles was assessed by atomic force microscopy (AFM). The treated blocks were subjected to a 5-time 120s/day citric acid at pH 3.2 for 14 days. Dentine microhardness loss, dentine surface loss, crystal characteristics and surface morphologies were assessed using microhardness test, non-contact profilometry, X-ray diffraction (XRD) and scanning electron microscopy (SEM), respectively. Data of dentine hardness loss and dentine surface loss were analysed by one-way ANOVA and Tukey’s multiple comparison post hoc test.
Results: AFM revealed salivary protein clumped on dentine block surface in Groups 1 and 2. Dentine microhardness loss (±SD in %) in Groups 1 to 3 were 15.20 ± 2.18, 17.42 ± 2.10, and 28.17 ± 2.20, respectively (Groups 1=2<3; p<0.001). The dentine surface loss (±SD in μm) in Groups 1 to 3 were 4.75 ± 0.28, 4.62 ± 0.33, and 9.66 ± 0.32, respectively (Groups 1=2<3; p<0.001). XRD analysis showed silver chloride, silver phosphate and silver fluoride formed in Group 1, ammonium fluoride, sodium fluoride and calcium fluoride formed in Group 2, while only hydroxyapatite were detected in Group 3. SEM revealed dentinal tubular occlusion in Groups 1-2 and exposed dentinal tubules in Group 3.
Conclusions: A one-off application of 38% SDF with salivary pellicle had promising results initial outcome similar to stannous chloride-containing fluoride in preventing human dentine erosion.