IADR Abstract Archives
Effect of Silver Diamine Fluoride on Vital Dental Pulp: a Systematic Review
Objectives: The objective of this study is to review systematically the literature on the biological effect of silver diamine fluoride (SDF) on dental pulp.
Methods: An extensive search was performed using the terms (silver diamine fluoride) OR (silver diammine fluoride) OR (diamine silver fluoride) OR (diammine silver fluoride) OR (DSF) OR (SDF) AND (dental pulp) OR (capping) in the ProQuest, PubMed, SCOPUS, and Web of Science databases. Animal studies, clinical studies, and case reports investigating the effect of SDF on vital dental pulp were included.
Results: The initial search identified 1,273 publications, of which four publications met the inclusion criteria. These four publications reported the effect of direct or indirect SDF application on vital pulp of teeth. Direct SDF application on vital pulp caused pulp necrosis. Indirect SDF application caused inconspicuous or mild inflammatory response of dental pulp. The odontoblasts in the dental pulp showed increased cellular activity. Tertiary dentine was formed in the pulpal side of the cavity with indirect SDF application. Accentuated incremental lines of tertiary dentine reflected disturbances in mineralisation. Silver ions were found to penetrate along the dentinal tubules but were not detected inside the pulp in each of the four included studies.
Conclusions: : The number of studies that assessed the biological effect of SDF on dental pulp was limited. They suggested direct SDF application caused pulp necrosis. Indirect SDF application could elicit mild inflammation of the pulp. It promoted a protective response in the dentin–pulp complex with increased odontoblastic activity and tertiary dentine formation.
Methods: An extensive search was performed using the terms (silver diamine fluoride) OR (silver diammine fluoride) OR (diamine silver fluoride) OR (diammine silver fluoride) OR (DSF) OR (SDF) AND (dental pulp) OR (capping) in the ProQuest, PubMed, SCOPUS, and Web of Science databases. Animal studies, clinical studies, and case reports investigating the effect of SDF on vital dental pulp were included.
Results: The initial search identified 1,273 publications, of which four publications met the inclusion criteria. These four publications reported the effect of direct or indirect SDF application on vital pulp of teeth. Direct SDF application on vital pulp caused pulp necrosis. Indirect SDF application caused inconspicuous or mild inflammatory response of dental pulp. The odontoblasts in the dental pulp showed increased cellular activity. Tertiary dentine was formed in the pulpal side of the cavity with indirect SDF application. Accentuated incremental lines of tertiary dentine reflected disturbances in mineralisation. Silver ions were found to penetrate along the dentinal tubules but were not detected inside the pulp in each of the four included studies.
Conclusions: : The number of studies that assessed the biological effect of SDF on dental pulp was limited. They suggested direct SDF application caused pulp necrosis. Indirect SDF application could elicit mild inflammation of the pulp. It promoted a protective response in the dentin–pulp complex with increased odontoblastic activity and tertiary dentine formation.