IADR Abstract Archives

Patient-Specific Estimation of Bone-Graft Volume for Sinus Augmentation Using CBCT

Objectives: To estimate the bone-graft volumes needed for sinus floor elevation (SFE) for various elevation heights at the maxillary first (MM1) and/or second molar (MM2) sites using cone-beam computed tomography (CBCT), and to develop bone-graft volume prediction models based on the augmentation site, elevation height, and sinus width.
Methods: CBCT scans with a medium-to-large field-of-view, performed at the Diagnostic Imaging Clinic, HKU Faculty of Dentistry, were screened for inclusion. Ten defined regions, above the MM1 and MM2 sites, in each maxillary sinus were semi-automatically segmented from the included CBCTs, and their volumes were automatically measured using the ITK-SNAP program. The sinus widths at the height ranging between 8-16mm from the sinus floor were measured at the the MM1 and MM2 sites, respectively. Multiple linear regression analyses were performed to evaluate the association of the bone-graft volume estimated for SFE at different augmentation sites with elevation height and sinus width.
Results: In total, 224 sinuses on 133 scans were included. For the same elevation height, the mean graft volume estimated for SFE at the MM1 site were greater than that at the MM2 site. The estimated graft volume was significantly associated with elevation height and sinus width (all p-values<0.001). Three prediction models proposed explained 89-91% of the variation in the estimated bone-graft volumes. The mean absolute deviations and absolute percentage deviations between the measured and predicted volumes ranged from 0.12-0.28cm3 and from 9.78-10.62%, respectively.
Conclusions: Elevation height and sinus width are strong predictors of the bone-graft volume. The proposed prediction models may enable more patient-specific estimation of the bone-graft volume needed for SFE, which could facilitate the preparation of an adequate amount of bone-graft to avoid insufficient elevation of the sinus floor, and improve patient-clinician communication about the cost of bone-graft material.

2021 South East Asian Division Meeting (Hong Kong)
Hong Kong
2021
019
Oral & Maxillofacial Surgery Research
  • Hung, Kuo-feng  ( Faculty of Dentistry, the University of Hong Kong , Hong Kong , Hong Kong )
  • Hui, Liuling  ( Faculty of Dentistry, the University of Hong Kong , Hong Kong , Hong Kong )
  • Leung, Yiu Yan  ( Faculty of Dentistry, the University of Hong Kong , Hong Kong , Hong Kong )
  • NONE
    Poster Session
    Oral & Maxillofacial Surgery Research
    Wednesday, 12/08/2021 , 12:00PM - 01:00PM
    Table 2. Multiple linear regression analyses of the association of the graft volume estimated for sinus floor elevation at different augmentation sites with elevation height and sinus width as predictor variables
     B95% CI
    (lower, upper limit)
    p valueAdjusted R2Bone-graft volume prediction model
    Maxillary first molar site
    Intercept-1.585(-1.651, -1.523)<0.0010.901V(M1) = 0.132H + 0.069W(M1) – 1.585
    Sinus width0.069(0.066, 0.073)<0.001
    Elevation height0.069(0.128, 0.137)<0.001
    Maxillary second molar site
    Intercept-1.470(-1.527, -1.418)<0.0010.913V(M2) = 0.134H + 0.066W(M2) – 1.470
    Sinus width0.066(0.062, 0.069)<0.001
    Elevation height0.134(0.130, 0.137)<0.001
    Maxillary first and second molar sites
    Intercept-2.652(-2.775, -2.525)<0.0010.891V(M1M2) = 0.279H + 0.1W(M1M2) – 2.652
    Sinus width0.10(0.093, 0.108)<0.001
    Elevation height0.279(0.269, 0.288)<0.001
    CI, confidence interval; B, beta coefficient; R2, coefficient of determination; H: expected elevation height (mm) in the range of 8 to 16 mm; W(M1): sinus width (mm) at the expected elevation height as measured at the maxillary first molar site, in the range of 10.6 to 36.6 mm; W(M2): sinus width (mm) at the expected elevation height as measured at the maxillary second molar site, in the range of 9.7 to 29.9 mm; W(M1M2): sinus width (mm) at the expected elevation height as measured at the interproximal surface between the maxillary first and second molars, in the range of 12.4 to 33.9 mm; V(M1): bone-graft volume (cm3) predicted for SFE at the maxillary first molar site; V(M2): bone-graft volume (cm3) predicted for SFE at the maxillary second molar site; V(M1M2): bone-graft volume (cm3) predicted for SFE at the maxillary first and second molar sites
    Table1. The bone-graft volumes estimated for sinus floor elevation for different elevation heights as measured at different augmentation sites
    Measurement siteElevation height in mmSegmentation (refer to Fig.1a)Estimated bone-graft volumes in cm3
    Mean±SD (95% CI)
    Regions in the sinus above
    the maxillary first molar
    8R10.73±0.19 (0.71-0.76)
    10R1+R21.05±0.25 (1.02-1.09)
    12R1+R2+R31.40±0.32 (1.36-1.44)
    14R1+R2+R3+R41.77±0.39 (1.72-1.82)
    16R1+R2+R3+R4+R52.16±0.45 (2.10-2.22)
    Regions in the sinus above
    the maxillary second molar
    8R60.68±0.14 (0.66-0.70)
    10R6+R70.98±0.19 (0.96-1.00)
    12R6+R7+R81.30±0.23 (1.27-1.33)
    14R6+R7+R8+R91.64±0.27 (1.61-1.68)
    16R6+R7+R8+R9+R102.00±0.32 (1.96-2.04)
    Regions in the sinus above
    the maxillary first and
    second molars
    8R1+R61.41±0.28 (1.37-1.45)
    10R1+R2+R6+R72.03±0.37 (1.98-2.08)
    12R1+R2+R3+R6+R7+R82.71±0.46 (2.65-2.77)
    14R1+R2+R3+R4+R6+R7+R8+R93.42±0.56 (3.34-3.49)
    16R1+R2+R3+R4+R5+R6+R7+R8+R9+R104.16±0.65 (4.07-4.25)
    SD, standard deviation; CI, confidence interval