IADR Abstract Archives
Masticatory Performance, TNF-a Serum Level and Score MoCA-INA in Elderly With Alzheimer's Disease
Objectives: The masticatory function is a risk factor for altering cognitive function. This study was to examine the differentiation frequency of mastication, time per cycle, masticatory efficiency, serum TNF-a and MoCA-INA between the elderly with AD and normal. Subsequently, to evaluate the correlation between variables.
Methods: the cross-sectional study design to explore correlation within components of masticatory performance, TNF-a serum level, and MoCA-INA score. The participants asked to chew the color-changeable chewing gum for 2 minutes. The blood test to examine TNF-a serum. MoCA test was performed to screening cognitive function. The Mann Whitney test and Spearman’s rho correlation for a nonparametric correlation test with a significant p-value < 0.05
Results: Fifty-one elderly as participants in this study (23 Alzheimer and 28 healthy subjects; mean age ± SD 73.52 ± 8.339 and 72.39 ± 7.420; mean the present teeth ± SD 20.26±6.099 dan 21.18 ± 4.722). Frequency of mastication (p>0.05), time per cycle (p>0.05), masticatory efficiency (p< 0.05), TNF-a serum level (p< 0.05) and MoCA-INA score (p<0.05) were different between groups. In this study, it has been observed that frequency of mastication, r= 0.344 (p<0.05); time per cycle, r= -0.347 (p<0.05); masticatory efficiency, r=0.360 (p<0.05) and TNF-a serum level, r= 0.343 (P<0.05) correlated with score of < MoCA-INA.
Conclusions: The frequency, time per cycle, masticatory efficiency, and serum TNF-a play the role of mastication pattern in the elderly, especially elderly with dementia Alzheimer.
Methods: the cross-sectional study design to explore correlation within components of masticatory performance, TNF-a serum level, and MoCA-INA score. The participants asked to chew the color-changeable chewing gum for 2 minutes. The blood test to examine TNF-a serum. MoCA test was performed to screening cognitive function. The Mann Whitney test and Spearman’s rho correlation for a nonparametric correlation test with a significant p-value < 0.05
Results: Fifty-one elderly as participants in this study (23 Alzheimer and 28 healthy subjects; mean age ± SD 73.52 ± 8.339 and 72.39 ± 7.420; mean the present teeth ± SD 20.26±6.099 dan 21.18 ± 4.722). Frequency of mastication (p>0.05), time per cycle (p>0.05), masticatory efficiency (p< 0.05), TNF-a serum level (p< 0.05) and MoCA-INA score (p<0.05) were different between groups. In this study, it has been observed that frequency of mastication, r= 0.344 (p<0.05); time per cycle, r= -0.347 (p<0.05); masticatory efficiency, r=0.360 (p<0.05) and TNF-a serum level, r= 0.343 (P<0.05) correlated with score of < MoCA-INA.
Conclusions: The frequency, time per cycle, masticatory efficiency, and serum TNF-a play the role of mastication pattern in the elderly, especially elderly with dementia Alzheimer.