IADR Abstract Archives
Serum Vitamin D, Calcium, Alkaline Phosphatase and Parathyroid Hormone Level in Chronic Periodontitis and Healthy Periodontium
Objectives: To compare serum vitamin D, calcium, alkaline phosphatase and parathyroid hormone levels in patients with periodontitis and healthy periodontium and find out if any correlation exists between their level and periodontal diseases
Methods: comparative study was done in 80 patients visiting Department of Dental Surgery, Bir Hospital, National Academy of Medical Sciences, Kathmandu, Nepal. Parameters measured were plaque index, gingival index, clinical attachment level and pocket depth for the presence of healthy periodontium and chronic periodontitis. Blood investigations for serum Vitamin D, calcium, alkaline phophatase (ALP) and parathyroid hormone (PTH) level were obtained.
Data were analysed using IBM SPSS Statistics for Windows, version 26 (IBM Corp., Armonk, N.Y., USA) software and independent t-test was used for comparing the mean of serum vitamin D, calcium, ALP and PTH level between healthy and chronic periodontitis patients and compare between male and female and ANOVA were used for analysis of the mean level of serum Vitamin D, calcium, ALP and PTH level between different age groups.
Results: Out of total 80 patients enrolled, 40 patients had healthy periodontium and 40 were with chronic periodontitis mean age of 36.20±7.37 years. Mean level of serum vitamin D (p=0.123), Calcium (p=0.227), ALP (p=0.671) and PTH (p= 0.460) were statistically insignificant when compared in sex. Mean levels of serum Vitamin D (p=0.006), calcium (p=0.020) were statistically significant and ALP (p=0.267) and PTH (p=0.351) were statistically insignificant between patients with healthy periodontium and chronic periodontitis.
Conclusions: Within the limitation of this study, it is concluded there is no differences in the level of serum ALP and PTH between the chronic periodontitis and healthy patients and higher level of serum vitamin D and calcium were seen in the chronic periodontitis patients as compared to healthy patients. Thus, no association was seen with the level of serum vitamin D, calcium, ALP and PTH and chronic periodontitis
Methods: comparative study was done in 80 patients visiting Department of Dental Surgery, Bir Hospital, National Academy of Medical Sciences, Kathmandu, Nepal. Parameters measured were plaque index, gingival index, clinical attachment level and pocket depth for the presence of healthy periodontium and chronic periodontitis. Blood investigations for serum Vitamin D, calcium, alkaline phophatase (ALP) and parathyroid hormone (PTH) level were obtained.
Data were analysed using IBM SPSS Statistics for Windows, version 26 (IBM Corp., Armonk, N.Y., USA) software and independent t-test was used for comparing the mean of serum vitamin D, calcium, ALP and PTH level between healthy and chronic periodontitis patients and compare between male and female and ANOVA were used for analysis of the mean level of serum Vitamin D, calcium, ALP and PTH level between different age groups.
Results: Out of total 80 patients enrolled, 40 patients had healthy periodontium and 40 were with chronic periodontitis mean age of 36.20±7.37 years. Mean level of serum vitamin D (p=0.123), Calcium (p=0.227), ALP (p=0.671) and PTH (p= 0.460) were statistically insignificant when compared in sex. Mean levels of serum Vitamin D (p=0.006), calcium (p=0.020) were statistically significant and ALP (p=0.267) and PTH (p=0.351) were statistically insignificant between patients with healthy periodontium and chronic periodontitis.
Conclusions: Within the limitation of this study, it is concluded there is no differences in the level of serum ALP and PTH between the chronic periodontitis and healthy patients and higher level of serum vitamin D and calcium were seen in the chronic periodontitis patients as compared to healthy patients. Thus, no association was seen with the level of serum vitamin D, calcium, ALP and PTH and chronic periodontitis