IADR Abstract Archives
Identifying Comorbidities among Dental Hospital Attendees with Self-Reported Systemic Health
Objectives: Periodontal disease is closely linked to various systemic diseases. This study investigated the potential comorbidities of common noncommunicable diseases in dental hospital attendees with self-reported systemic health.
Methods: Of 2,369 attendees at PPDH, 587 Chinese subjects (35-75 yrs) were selected and screened to meet the inclusion criteria: i) self-reported systemic health, ii) absence of medical diagnoses, and iii) no diagnostic tests within one year. 106 subjects (72 females and 34 males) were then recruited, and all completed the questionnaire of demographic characteristics, social-economic status and lifestyles. Full-mouth periodontal condition and bone level were assessed. According to CDC/AAP criteria and Bone loss/age (<0.5 or ≥0.5), the subjects were classified as groups with low or high susceptibility to severe periodontitis. Routine medical examination was undertaken, and blood/urine samples were collected. Echocardiography and pulse wave velocity were performed. Totally, 14 diagnostic tests were employed to identify obesity, diabetes, dyslipidemia, hypertension, hyperuricemia, cardiovascular disease and chronic kidney disease.
Results: There were 64 (60%) and 42 (40%) of subjects at the Low or High Susceptibility Groups respectively. 94% of them presented at least one abnormal results of the diagnostic tests/comorbidities, and those without any comorbidities (6%) were all from the Low Susceptibility Group. 42% exhibited 1-4 comorbidities, and 52% had ≥5 comorbidities, with significantly different distributions in subjects with low (1-4 vs ≥5: 51% vs 40%) and high susceptibility to severe periodontitis (1-4 vs ≥5: 29% vs 71%, p=0.008). Moreover, the susceptibility to severe periodontitis was associated with the comorbidity profiles following adjustments of 13 potential confounders (0-4 vs ≥5; OR 3.09, p=0.050).
Conclusions: This study suggests that periodontal condition may to some extent reflect the potential profile of systemic comorbidities. Poor periodontal status may be an alarm to the self-reported healthy subjects for early detection of undiagnosed comorbidities and appropriate healthcare.
Methods: Of 2,369 attendees at PPDH, 587 Chinese subjects (35-75 yrs) were selected and screened to meet the inclusion criteria: i) self-reported systemic health, ii) absence of medical diagnoses, and iii) no diagnostic tests within one year. 106 subjects (72 females and 34 males) were then recruited, and all completed the questionnaire of demographic characteristics, social-economic status and lifestyles. Full-mouth periodontal condition and bone level were assessed. According to CDC/AAP criteria and Bone loss/age (<0.5 or ≥0.5), the subjects were classified as groups with low or high susceptibility to severe periodontitis. Routine medical examination was undertaken, and blood/urine samples were collected. Echocardiography and pulse wave velocity were performed. Totally, 14 diagnostic tests were employed to identify obesity, diabetes, dyslipidemia, hypertension, hyperuricemia, cardiovascular disease and chronic kidney disease.
Results: There were 64 (60%) and 42 (40%) of subjects at the Low or High Susceptibility Groups respectively. 94% of them presented at least one abnormal results of the diagnostic tests/comorbidities, and those without any comorbidities (6%) were all from the Low Susceptibility Group. 42% exhibited 1-4 comorbidities, and 52% had ≥5 comorbidities, with significantly different distributions in subjects with low (1-4 vs ≥5: 51% vs 40%) and high susceptibility to severe periodontitis (1-4 vs ≥5: 29% vs 71%, p=0.008). Moreover, the susceptibility to severe periodontitis was associated with the comorbidity profiles following adjustments of 13 potential confounders (0-4 vs ≥5; OR 3.09, p=0.050).
Conclusions: This study suggests that periodontal condition may to some extent reflect the potential profile of systemic comorbidities. Poor periodontal status may be an alarm to the self-reported healthy subjects for early detection of undiagnosed comorbidities and appropriate healthcare.