Tomato (Solanum lycopersicum L.) Patch as an Alternative Dental Bleaching
Objectives: Tomato is known for its tooth whitening potency. Previous studies showed that pure tomato juice could remove tooth stains. However, it needs to be formulated into a more applicable dosage form. The aims of this study were to establish teeth whitening patch containing tomato juice as the active ingredient and to observe its dental bleaching effect. Furthermore, to evaluate this patch consists of HPMC-PVP-polymeric-combination-based matrix layer and polyurethane-based impermeable backing layer.
Methods: Tomato juice patches were divided into three groups with various concentrations; F1: 55%; F2: 60%; and F3: 65% (w/w). Patch contains 12% hydrogen peroxide (C) was used as a control group. The matrix layer of the patches was prepared using solvent casting method in 40°C for 18h, meanwhile the backing layer using Tegaderm™. Functional-properties of patches, surface pH, folding-endurance, and residence-time, were evaluated. For dental whitening analysis, each group of patches was applied on labial side of anterior stained teeth (n=6/group) for 3h and was repeated for 14 times. The teeth lightness was observed using digital dental photo CIEL*a*b* analysis method. Meanwhile, the teeth porosity was examined using SEM.
Results: All patches showed a durable residence-time (>3h) and a good folding endurance (>300). Although, the level of acidity was still high (pH <5) compared to critical pH of enamel (pH 5.2-5.8) and dentine (pH 6.0-6.8) demineralization. We found that the application of tomato patches enhanced the lightness of the teeth. Among all, F3 has made the greatest lightness and significantly enhance lightness compare to control patch (p<0.05). Moreover, the teeth porosity examination by SEM showed that application of 65% tomato patch caused less erosion compare to 12% hydrogen peroxide patch.
Conclusions: Tomato juice patch has been proven to increase teeth lightness with less erosion. Further research is needed to optimize its formulation and potentiality.