The Role of Calcium in Anadara granosa Shell Grafts to Osteocalcin Cells in Bone Formation
Objectives: This study aimed to analyze the effect of Anadara granosa graft to the expression of osteocalcin in the process of bone formation at day 15. Methods: The experimental units used were 21 male Wistar rats were divided into 3 groups: negative control group (K-) is a group without a graft applications, positive control group (K +) is a group with the graft application with bovine graft and a treatment group (P) was the group with the graft applications Anadara granosa. Osteocalcin expression was measured by histopathology preparations anatomy with IHC staining. Data were analyzed with Mann-Whitney test. Results: showed a significant difference in group K - with K + (p = 0.004) and group K - with P (p = 0.001) but there were no significant difference between K + group with P (p = 0.473). Conclusions: Anadara granosa graft increased the expression of osteocalcin in the process of bone formation at day 15.
Division: South East Asian Division Meeting
Meeting:2017 South East Asian Division Meeting (Taipei, Taiwan) Location: Taipei, Taiwan
Year: 2017 Final Presentation ID:0066 Abstract Category|Abstract Category(s):Dental Materials 5: Biocompatibility, Bioengineering and Biologic Effects of Materials
Authors
Kurniawan, Hansen
( Hang Tuah University
, Surabaya
, Jawa Timur
, Indonesia
)
Soemarno, Widyastuti
( Hang Tuah University
, Surabaya
, Jawa Timur
, Indonesia
)