IADR Abstract Archives
The Role of Calcium in Anadara granosa Shell Grafts to Osteocalcin Cells in Bone Formation
Objectives: This study aimed to analyze the effect of Anadara granosa graft to the expression of osteocalcin in the process of bone formation at day 15.
Methods: The experimental units used were 21 male Wistar rats were divided into 3 groups: negative control group (K-) is a group without a graft applications, positive control group (K +) is a group with the graft application with bovine graft and a treatment group (P) was the group with the graft applications Anadara granosa. Osteocalcin expression was measured by histopathology preparations anatomy with IHC staining. Data were analyzed with Mann-Whitney test.
Results: showed a significant difference in group K - with K + (p = 0.004) and group K - with P (p = 0.001) but there were no significant difference between K + group with P (p = 0.473).
Conclusions: Anadara granosa graft increased the expression of osteocalcin in the process of bone formation at day 15.
Methods: The experimental units used were 21 male Wistar rats were divided into 3 groups: negative control group (K-) is a group without a graft applications, positive control group (K +) is a group with the graft application with bovine graft and a treatment group (P) was the group with the graft applications Anadara granosa. Osteocalcin expression was measured by histopathology preparations anatomy with IHC staining. Data were analyzed with Mann-Whitney test.
Results: showed a significant difference in group K - with K + (p = 0.004) and group K - with P (p = 0.001) but there were no significant difference between K + group with P (p = 0.473).
Conclusions: Anadara granosa graft increased the expression of osteocalcin in the process of bone formation at day 15.