IADR Abstract Archives
Association Between Periodontitis and Psoriatic Arthritis in Taiwanese Population
Objectives: Psoriatic arthritis (PsA) has been defined as an inflammatory arthritis associated with psoriasis characterized by inflammation of the dermis and epidermis with predominantly skin and joint manifestations. The aim of this nationwide population-based retrospective cohort study was to assess the risk of periodontitis in patients with PsA.
Methods: Patients with newly diagnosed psoriatic disease from 2003 to 2012 were identified from Taiwanese National Health Insurance Research Database. The 1:4 ratio propensity score matched controls were selected from no PsA participations. The subsequent risk of periodontitis was evaluated in exposure group and comparison group. Multiple Cox proportional hazard models were used for the estimation.
Results: A total of 552 PsA patients were identified. The adjusted hazard ratio (aHRs) of periodontitis was 1.74 (1.22-2.48) in PsA group. The cumulative incidence proportion of periodontitis was higher in PsA group (log rank p=0.0072). In the stratified follow up duration analysis, the risk of periodontitis was significantly higher by 1.19 and 1.86 fold during the first 11 months and the subsequent 12 months, respectively, in the PsA cohort compared with the comparison cohort.
Conclusions: The increased risk of periodontitis was observed among Taiwanese patients with PsA.
Methods: Patients with newly diagnosed psoriatic disease from 2003 to 2012 were identified from Taiwanese National Health Insurance Research Database. The 1:4 ratio propensity score matched controls were selected from no PsA participations. The subsequent risk of periodontitis was evaluated in exposure group and comparison group. Multiple Cox proportional hazard models were used for the estimation.
Results: A total of 552 PsA patients were identified. The adjusted hazard ratio (aHRs) of periodontitis was 1.74 (1.22-2.48) in PsA group. The cumulative incidence proportion of periodontitis was higher in PsA group (log rank p=0.0072). In the stratified follow up duration analysis, the risk of periodontitis was significantly higher by 1.19 and 1.86 fold during the first 11 months and the subsequent 12 months, respectively, in the PsA cohort compared with the comparison cohort.
Conclusions: The increased risk of periodontitis was observed among Taiwanese patients with PsA.