IADR Abstract Archives
Association between Fluoride Varnish Application and Risk of Endodontic Treatments
Objectives: In Taiwan, a non-fluoridation country, the incidence rate (more than 40%) between 3-year-old children to 6-year-old children was a huge challenge to diminish. Since 2004, Taiwan government provided topical fluoride varnish applications for children under 5-year-old. The objective of the present study was to investigate the association between topical fluoride varnish applications provided from the government and the subsequent risk of endodontic treatments among primary molars, using national health insurance research database.
Methods: The current retrospective cohort study recruited participants who were younger than 6 years of age during 2004–2013. Children who received topical fluoride varnish applications more than 4 times without any dental treatments within 2 years after the first time as “pure topical fluoride varnish application group.” After 1:2 matching process, 3,644 children in the “pure fluoride varnish group” and 7,288 children in non-exposed group were selected for further analysis. These 10,932 participants were followed to see if they would receive pulpotomy and pulpectomy in their primary molars until aged 8 or the end of the study (December 31, 2013). Cox proportional hazards models were employed to estimate the effect of having fluoride varnish applications on the risk of endodontic treatments.
Results: 3.98% children from “pure fluoride varnish group” received subsequent pulpotomy or pulpectomy, which was significnantly fewer than 7.23% from children who never received topical fluoride varnish applications (P < 0.0001). After adjusting for potential confounding factors, the adjusted hazard ratio for endodontic treatments in primary molars for the “pure topical fluoride varnish application group” was 0.51 (95% CI = 0.41–0.64, P < 0.0001) compared to those who never received topical fluoride varnish applications.
Conclusions: The multivariate Cox proportional hazard regression model analysis revealed that the participants who had received topical fluoride varnish application were associated with lower risk of future endodontic treatments.
Methods: The current retrospective cohort study recruited participants who were younger than 6 years of age during 2004–2013. Children who received topical fluoride varnish applications more than 4 times without any dental treatments within 2 years after the first time as “pure topical fluoride varnish application group.” After 1:2 matching process, 3,644 children in the “pure fluoride varnish group” and 7,288 children in non-exposed group were selected for further analysis. These 10,932 participants were followed to see if they would receive pulpotomy and pulpectomy in their primary molars until aged 8 or the end of the study (December 31, 2013). Cox proportional hazards models were employed to estimate the effect of having fluoride varnish applications on the risk of endodontic treatments.
Results: 3.98% children from “pure fluoride varnish group” received subsequent pulpotomy or pulpectomy, which was significnantly fewer than 7.23% from children who never received topical fluoride varnish applications (P < 0.0001). After adjusting for potential confounding factors, the adjusted hazard ratio for endodontic treatments in primary molars for the “pure topical fluoride varnish application group” was 0.51 (95% CI = 0.41–0.64, P < 0.0001) compared to those who never received topical fluoride varnish applications.
Conclusions: The multivariate Cox proportional hazard regression model analysis revealed that the participants who had received topical fluoride varnish application were associated with lower risk of future endodontic treatments.