IADR Abstract Archives
A retrospective study of metastatic tumors to the oral and maxillofacial areas
Objectives: The objective of this study is to retrospective review the patients with diagnosis of metastatic tumors to the oral and maxillofacial areas and to study their demographic, clinical, pathologic features.
Methods: Biopsy reports from the department of Oral Pathology, Faculty of Dentistry, Chulalongkorn University from 1997 to 2016 were reviewed for identification of patients with metastatic tumors to the oral and maxillofacial areas. Information regarding age, gender, lesion location, signs and symptoms, radiographic features, and histologic diagnoses was recorded. The H&E and immunohistochemical slides from all cases were reviewed by pathologist to confirm the original diagnosis. Descriptive data analysis was performed using the Excel version 2013.
Results: Fourteen cases of metastatic tumors were identified and they presented with an average age of 59.43 year with a male to female ratio of 1:1.33. The jaw bone was the most frequently affected location (10/14), with the posterior mandible being the most common site (8/14). Paresthesia of the lower lip was the most common chief complaint, seen in patients with the lesions at the posterior mandible (6/8). The primary malignant site was reported at the time of patient presentation with the oral metastatic lesions in 7 cases, including breast, brain, liver (2), lung and thyroid gland (2), whereas 7 cases suggested the indication of unknown primary cancer. Of those 7 cases, 5 cases were adenocarcinoma.
Conclusions: The findings of this study indicate that the metastatic tumors to the oral and maxillofacial areas are rare. Oral metastatic tumors may be the first indication of an undiscovered cancer at a distant primary site.
Methods: Biopsy reports from the department of Oral Pathology, Faculty of Dentistry, Chulalongkorn University from 1997 to 2016 were reviewed for identification of patients with metastatic tumors to the oral and maxillofacial areas. Information regarding age, gender, lesion location, signs and symptoms, radiographic features, and histologic diagnoses was recorded. The H&E and immunohistochemical slides from all cases were reviewed by pathologist to confirm the original diagnosis. Descriptive data analysis was performed using the Excel version 2013.
Results: Fourteen cases of metastatic tumors were identified and they presented with an average age of 59.43 year with a male to female ratio of 1:1.33. The jaw bone was the most frequently affected location (10/14), with the posterior mandible being the most common site (8/14). Paresthesia of the lower lip was the most common chief complaint, seen in patients with the lesions at the posterior mandible (6/8). The primary malignant site was reported at the time of patient presentation with the oral metastatic lesions in 7 cases, including breast, brain, liver (2), lung and thyroid gland (2), whereas 7 cases suggested the indication of unknown primary cancer. Of those 7 cases, 5 cases were adenocarcinoma.
Conclusions: The findings of this study indicate that the metastatic tumors to the oral and maxillofacial areas are rare. Oral metastatic tumors may be the first indication of an undiscovered cancer at a distant primary site.