Efficiency of Shellac F Varnish in Caries Prevention Among 12-year-old Children

Objectives: The objective of this study was to evaluate clinical efficiency of Shellac F in caries prevention among 12-year-old children living in non-fluoridated area in HoChiMinh city, VietNam.
Methods: A single-blind, randomized controlled trial was conducted in 207 children with 12 ages living in a non-fluoridated area in HoChiMinh city, Vietnam. The children were randomly divided into 3 groups. Group 1 was applied Shellac F, Group 2 was used Duraphat^®,, and Group 3 was not received any fluoride varnishes during the study. Oral hygiene Regimens and Oral health education were implemented in the same manner in 3 groups. Experiment Fluoride Varnishes were applied every 3 months for subjects in group 1 and 2 during 24 months. Dental caries was recorded every six months using ICDAS II by 3 calibrated examiners. Caries experiences were calculated in S1 level (Non-Cavitated lesions) and S3 level (Cavitated lesions). One-way ANOVA and Repeated ANOVA were applied.
Results: Caries experiences among children in Shellac F group and Duraphat^® group were significantly lower than control group after 12, 18 and 24 months in S1 level (p<0.001). However, the significant differences were not found in S3 level (p>0.05). After 24 months, the percentages of caries reduction compared to control group were 52% (S1) and 37% (S3); and 56% (S1) and 12% (S3) in Shellac F group; and Duraphat^® group, respectively. There were no statistically significant differences in changes in caries experiences (S1 level and S2 level) in subjects after 12, 18 and 24 months between Shellac F Group and Duraphat one (p>0.05).
Conclusions: Shellac F showed its efficiency being similar with Duraphat in caries prevention among 12 year-old children living in non-fluoriated area.