IADR Abstract Archives
Evaluation on Residual Monomer of HDDMA Matrix System of FRC
Objectives: It was reported that matrix system based on bis-GMA was hazardous. Alternative monomers such as 1,6-Hexanediol dimethacrylate (HDDMA) is under current research. The aim of this research was to evaluate residual monomer content of HDDMA based matrix compositions on FRC.
Methods: Three monomer compositions based on bis-GMA (Sigma-Aldrich, USA), methylmethacrylate(MMA) (ProSciTech, Australia), HDDMA (Esstech, USA), and camphorquinone(CQ) (Esstech, USA), N,N-cyanoethyl methylaniline(CEMA) (Esstech, USA), E-glass fibers (Stick Tech, Finland) were used. The ratio of the resin matrix (in weight %) were 78.4%bis-GMA+19.6%MMA+1%CQ+1%CEMA (control-group), 8.4%HDDMA+19.6%MMA+1%CQ+1%CEMA (EXP-1group), and 49%HDDMA+49%MMA+1%CQ+1%CEMA (EXP-2group). Samples with fibers were embedded in matrix, light-cured, then powdered. Powder of 150mg was diluted in acetonitrile to 10ml. Magnetic stirrer was used to dissolve the solution (72h). The solution was filtered, then injected into the HPLC for 20µL. Residual monomer content was evaluated using the mobile phase of acetonitrile and water with a 7:3 ratio, flow rate 1mL/minute at room temperature. The size of column was C185µm, length 125mm, and 4mm in diameter. UV detection used 275nm. The data were analyzed by one way ANOVA.
Results: The average of residual monomer contents measurement showed (in %): 0.02125±0.00018 (control-group), 0.01660±0.00016 (EXP-1group), 0.01676±0.00033 (EXP-2group). The ANOVA showed significant difference of monomer content among the groups (p<0.05). The LSD test showed significant difference between EXP-1 and control-groups; and also between EXP-2 and control-groups (p<0.05); whilst no significant difference between EXP-1 and EXP-2 groups (p>0.05).
Conclusions: In conclusion, a resin matrix system based on HDDMA–MMA (EXP-1 and EXP-2 groups) revealed significant difference of residual monomer content to bis-GMA–MMA (control-group) system. The HDDMA-MMA matrix system was less residual monomer content than bis-GMA-MMA matrix system.
Methods: Three monomer compositions based on bis-GMA (Sigma-Aldrich, USA), methylmethacrylate(MMA) (ProSciTech, Australia), HDDMA (Esstech, USA), and camphorquinone(CQ) (Esstech, USA), N,N-cyanoethyl methylaniline(CEMA) (Esstech, USA), E-glass fibers (Stick Tech, Finland) were used. The ratio of the resin matrix (in weight %) were 78.4%bis-GMA+19.6%MMA+1%CQ+1%CEMA (control-group), 8.4%HDDMA+19.6%MMA+1%CQ+1%CEMA (EXP-1group), and 49%HDDMA+49%MMA+1%CQ+1%CEMA (EXP-2group). Samples with fibers were embedded in matrix, light-cured, then powdered. Powder of 150mg was diluted in acetonitrile to 10ml. Magnetic stirrer was used to dissolve the solution (72h). The solution was filtered, then injected into the HPLC for 20µL. Residual monomer content was evaluated using the mobile phase of acetonitrile and water with a 7:3 ratio, flow rate 1mL/minute at room temperature. The size of column was C185µm, length 125mm, and 4mm in diameter. UV detection used 275nm. The data were analyzed by one way ANOVA.
Results: The average of residual monomer contents measurement showed (in %): 0.02125±0.00018 (control-group), 0.01660±0.00016 (EXP-1group), 0.01676±0.00033 (EXP-2group). The ANOVA showed significant difference of monomer content among the groups (p<0.05). The LSD test showed significant difference between EXP-1 and control-groups; and also between EXP-2 and control-groups (p<0.05); whilst no significant difference between EXP-1 and EXP-2 groups (p>0.05).
Conclusions: In conclusion, a resin matrix system based on HDDMA–MMA (EXP-1 and EXP-2 groups) revealed significant difference of residual monomer content to bis-GMA–MMA (control-group) system. The HDDMA-MMA matrix system was less residual monomer content than bis-GMA-MMA matrix system.