HISTOLOGICAL EVALUATION OF BONE REPAIR USING ONE MEMBRANE AND A CALCIUM SULPHATE.
The aim of study was to evaluate histologically the alveolar bone repair post tooth extraction in cobayos using one collagen sponge membrane and a calcium sulfate graft. It was evaluated 24 cobayos divided in two groups of experimentation. Both groups underwent the extraction of mandibular premolars of both their hemiarch, under general anesthesia; a collagen membrane or the calcium sulfate graft was placed inside the tooth socket of one hemiarch of random way. The control tooth socket was washed with a placebo. The sacrifices were by anesthetic overdose to the 7, 14 and 30 days post tooth extraction. The volume fraction of the healing alveolar components: Blood clot(CS), granulation tissue(TG), provisional matrix(MP) and mineralized bone(HM), were determined using histological sections of each tooth socket by a differential point-counting method.There was a greater percentage in: CS 7 days, middle third, for calcium sulfate (81.11%); in MP 7 days, apical third, for collagen membrane (85.48%) and in HM 30 days, apical third for calcium sulfate (50.73%). There were statistically significant differences when comparing calcium sulfate with its control, in MP 14 days and HM 7 days (apical third), being greater the control and when comparing the collagen membrane with respect to calcium sulfate in CS (smaller for collagen membrane) and MP (greater for collagen membrane) 7 days, apical third. The statistically significant differences found but isolated for some of indicators in some periods of time and for both experimental groups contrasted with their tooth socket control reveals that the alveolar repair was similar for the studied groups.