IADR Abstract Archives
Postoperative Microcirculatory Changes In Human Gingiva After Tunnelling Technique
Objectives: Comparison of the effect of xenogenic collagen matrix (Mucograft) to the free connective tissue graft (CTG) on the microcirculation of the modified coronally advanced tunnel flap (MCAT).
Methods: In an exploratory study 4 women and 4 men received MCAT combined with either Mucograft or CTG from the palate. The clinical outcome after 6 months was evaluated. The gingival microcirculation was followed up 6 months by laser speckle contrast imaging and wound fluid was measured quantitatively.
Results: Reduction in recession depth and width were similar in both groups, but the keratinized tissue width at the Mucograft treated site was significantly less than in CTG. At the marginal gingiva the Mucograft treated sites showed rapid restoration of the blood flow in males followed by a hyperemic response, unlike females. The wound fluid production of the Mucograft treated site exceeded the CTG sites in females, but the opposite was found in males. Overall females had higher and prolonged wound fluid production.
Conclusions: The microcirculation of the minimal invasive MCAT restores quickly within 14 days. The recovery of graft bed circulation was not restrained by application of Mucograft. Gender may have an effect on blood flow and inflammation following mucogingival surgery, but this needs to be confirmed in further experiments.
Methods: In an exploratory study 4 women and 4 men received MCAT combined with either Mucograft or CTG from the palate. The clinical outcome after 6 months was evaluated. The gingival microcirculation was followed up 6 months by laser speckle contrast imaging and wound fluid was measured quantitatively.
Results: Reduction in recession depth and width were similar in both groups, but the keratinized tissue width at the Mucograft treated site was significantly less than in CTG. At the marginal gingiva the Mucograft treated sites showed rapid restoration of the blood flow in males followed by a hyperemic response, unlike females. The wound fluid production of the Mucograft treated site exceeded the CTG sites in females, but the opposite was found in males. Overall females had higher and prolonged wound fluid production.
Conclusions: The microcirculation of the minimal invasive MCAT restores quickly within 14 days. The recovery of graft bed circulation was not restrained by application of Mucograft. Gender may have an effect on blood flow and inflammation following mucogingival surgery, but this needs to be confirmed in further experiments.