The purpose of this study was the early detection of premalignant and malignant oral soft lesions by Fluorescent light (VELscope).
Method:
A total of 748 patients were evaluated through clinical and Fluorescent light analysis for the whole oral cavity. Any lesion was detected under went a surgical excision biopsy as the golden standard for the detection of the lesion’s histology, then a comparison between the results to assure the efficacy of the fluorescent light analysis outcome.
Result:
9.4% of the lesions detected were abnormal lesions 83.09% of which had loss of fluorescent light effect and with the use of the surgical biopsy the machine had a sensitivity of 74.1% and specificity of 96.3 %. According to the statistical analysis the P-value was much lower than 0.05, so we can conclude at 95% of confidence level that there were significant agreement between VELscope results and Biopsy results. Kappa coefficient value was approximately 0.5, this means that the strength of the agreement was Medium.
Conclusion:
The use of VELscope was considered as clinical diagnostic aid instrument in the detection of premalignant and malignant lesions of the oral cavity. In addition to that, it helped in the detection of the borders in both the surgical biopsy and surgical excision.