Radiological Comparison between  Bio-Oss and a New Deproteined Bovine Bone

Methods: Bovine bonewas deproteinated through suspension in an alkaline solution, and the remaining material was sterilized in powder form. Symmetrical segments of both parietal bones were surgically removed from 12 inbred New Zealand rabbits, and the defects were transplanted with the above preparation on one side and Bio-Oss on the other. The defect area was measured using radiography 3 months after transplantation. 

Results: One of the subjects died due to the hemorrhage during surgery, but there were no other short-term or long-term intra-operative or post-operative complications. After 3 months the defects on both sides were reduced or totally repaired and reduction in defect areas had no significant difference between the two sides.

Conclusions: The deproteinated bovine bone preparation used in our study had similar effects on the repair of parietal bone defects compared to Bio-Oss and thus may serve as an alternative for the treatment of such defects. furthur research is warranted to better determine its safety and efficacy.