IADR Abstract Archives

Histopathological Comparison between  Bio-Oss and a New Deproteined Bovine Bone

Objectives: Bone defects, mostly caused by tumor excision, fractures, cysts and aging, are a major concern in maxillofacial surgery. Effective but expensive grafts are available. The aim of this study was to compare the effect of transplantation of a new deproteinated bovine bone preparation with a similar conventional industrial product, Bio-Oss, on parietal bone regeneration.

Methods: Bovine bonewas deproteinated through suspension in an alkaline solution, and the remaining material was sterilized in powder form. Symmetrical segments of both parietal bones were surgically removed from 12 inbred New Zealand rabbits, and the defects were transplanted with the above preparation on one side and Bio-Oss on the other. The defect area was measured using light microscopy 4 weeks after transplantation. 

Results: After 4 weeks, the reduction in defect area had no significant difference between the two sides

Conclusions: The deproteinated bovine bone preparation used in our study had similar effects on the repair of parietal bone defects compared to Bio-Oss and thus may serve as an alternative for the treatment of such defects.

Pan European Region Meeting
2012 Pan European Region Meeting (Helisinki, Finland)
Helisinki, Finland
2012
169
Scientific Groups
  • Azimi Lisar, Hamidreza  ( Shahed University of Medical Sciences, Tehran, N/A, Iran )
  • Riazi, Haleh  ( Shahed University of Medical Sciences, Tehran, N/A, Iran )
  • Shalileh, Keivan  ( Tehran University of Medical Sciences, Tehran, N/A, Iran )
  • Sarabadani, Zahra  ( Shahed University of Medical Sciences, Tehran, N/A, Iran )
    • Poster Session
    Mineralized Tissue
    09/13/2012