IADR Abstract Archives
Characterization of the new Titanium Alloy Ti-20Zr-3Mo-3Sn for Dental Implants
Objectives: In the field of metallic biomaterials, and more particularly for titanium-based alloys, improvements in biocompatibility have been made in recent years to optimize the properties of medical devices. In oral implantology, particular attention has been focused on some β titanium alloys thanks to their modulus of elasticity which is generally lower than α and (α + β) type alloys. In this study, the new metastable β titanium alloy Ti2033 (Zr: 20% at, Mo 3% at and Sn: 3% at), was compared to the reference alloys Ti-6Al-4V and Ti-14Zr currently marketed for dental implants.
Methods: The Ti2033 alloy was synthesized by cold crucible levitation melting technique, was cold rolled and was punched into discs for biological evaluation. Then, specimens were finally treated in order to retain the β-phase in its metastable state. Tensile tests were performed to evaluate the mechanical properties of the samples. Cell viability assays were done using an MTT test with human-derived osteoblasts (SaOs-2) at 1, 3 and 7 days.
Results: The main mechanical characteristic of this alloy is a modulus of elasticity almost twice lower than conventional titanium alloys used in oral implantology and one of the lowest modulus of elasticity among β titanium alloys developed for medical applications. From a biological point of view, in vitro cell viability (SaOs-2) is similar (no significant difference) to the reference alloys Ti-6Al-4V and Ti-14Zr.
Conclusions: Given the mechanical properties of the Ti2033 alloy and the encouraging results of studies carried out on Ti-Zr alloys, this new alloy seems to be suitable for biomedical use. Other studies are still necessary to validate its first results, and functionalization tests are in progress.
Methods: The Ti2033 alloy was synthesized by cold crucible levitation melting technique, was cold rolled and was punched into discs for biological evaluation. Then, specimens were finally treated in order to retain the β-phase in its metastable state. Tensile tests were performed to evaluate the mechanical properties of the samples. Cell viability assays were done using an MTT test with human-derived osteoblasts (SaOs-2) at 1, 3 and 7 days.
Results: The main mechanical characteristic of this alloy is a modulus of elasticity almost twice lower than conventional titanium alloys used in oral implantology and one of the lowest modulus of elasticity among β titanium alloys developed for medical applications. From a biological point of view, in vitro cell viability (SaOs-2) is similar (no significant difference) to the reference alloys Ti-6Al-4V and Ti-14Zr.
Conclusions: Given the mechanical properties of the Ti2033 alloy and the encouraging results of studies carried out on Ti-Zr alloys, this new alloy seems to be suitable for biomedical use. Other studies are still necessary to validate its first results, and functionalization tests are in progress.