IADR Abstract Archives
Intraductal Irrigations and Sialoendoscopies Dual Treatment for Oral Dryness Relief
Objectives: To evaluate the combination of salivary gland intra-ductal irrigations (IG) followed by sialoendoscopy irrigations (SI) of the parotid gland on the improvement of salivary gland secretory dysfunction (SGSD).
Methods: The study included a retrospective analysis of the medical files of patients with SGSD who were treated by dual therapy of major salivary gland IG followed by SI during 2014–2020. Collected data included the following parameters: socio-demographics, systemic co-morbidities, signs, and symptoms. Improvement was assessed by comparing the mean unstimulated and stimulated whole salivary flow rate (UWSF, SWSF) from the baseline point (before IG procedure) to the last point (after SI) using repeated measures. The between-subjects effects of various factors and covariants were analyzed using repeated-measures ANCOVA.
Results: 100 patients were included with an age range of 15-83 years (mean age of 60.1±13.1 years). Improvement was detected on UWSF measurements (p=0.031, F=3.83), but not on SWSF measurements (p=0.165, F=1.85). The between-subjects effects on UWSF measurements were statistically significant for sex (p=0.003, F=9.526) and salivary gland manipulators use (p<0.001, F=15.107), and for the interaction between sex and salivary gland manipulators use (p=0.002, F=9.709).
Conclusions: The combination of IG followed by SI increases UWSF salivary secretion in SGSD patients, and therefore can be used as a novel treatment modality to treat oral dryness in SGSD cases resistant to treatment.
Methods: The study included a retrospective analysis of the medical files of patients with SGSD who were treated by dual therapy of major salivary gland IG followed by SI during 2014–2020. Collected data included the following parameters: socio-demographics, systemic co-morbidities, signs, and symptoms. Improvement was assessed by comparing the mean unstimulated and stimulated whole salivary flow rate (UWSF, SWSF) from the baseline point (before IG procedure) to the last point (after SI) using repeated measures. The between-subjects effects of various factors and covariants were analyzed using repeated-measures ANCOVA.
Results: 100 patients were included with an age range of 15-83 years (mean age of 60.1±13.1 years). Improvement was detected on UWSF measurements (p=0.031, F=3.83), but not on SWSF measurements (p=0.165, F=1.85). The between-subjects effects on UWSF measurements were statistically significant for sex (p=0.003, F=9.526) and salivary gland manipulators use (p<0.001, F=15.107), and for the interaction between sex and salivary gland manipulators use (p=0.002, F=9.709).
Conclusions: The combination of IG followed by SI increases UWSF salivary secretion in SGSD patients, and therefore can be used as a novel treatment modality to treat oral dryness in SGSD cases resistant to treatment.