IADR Abstract Archives
The Association Between Multisystem Inflammatory Syndrome and Oral Health Status in Children
Objectives: The aim of this cross-sectional study was to investigate oral health status in children with Multisystem Inflammatory Syndrome (MIS-C) compared to children with SARS-CoV-2 infection.
Methods: A total of 54 children with COVID-19 associated MIS-C (n=23) and mild COVID-19 (n=31) were recruited to the study (Age range: 5-15; gender (F/M): 23/31). Sociodemographic variables, medical examinations, oral hygiene habits as well as extra- and intra-oral findings (DMFT/dmft index, OHI scores and oral mucosal changes) were recorded.
Results: MIS-C was associated with cracked lips (all patients with MIS-C) and oral mucosal changes including erythema, white lesion and strawberry tongue and swelling of the gingiva compared to COVID-19 group (frequency of more than one mucosal change: 100% vs 35%) (p<0.001). MIS-C led to 45.8% increase in DMFT/dmft scores higher than 6 (DMFT/dmft (mean±SD): 5.52±3.16 (MIS-C) versus 2.26±1.80 (COVID-19) (p<0.01). Elevated OHI scores was associated with MIS-C (mean±SD: 3.06±1.02 (MIS-C) versus 2.41±0.97 (COVID-19) as well (p<0.05).
Conclusions: Oral manifestations mainly strawberry and erythematous tongue were predominantly associated with MIS-C. Oral/dental symptoms among children with MIS were prevalent. Therefore, dental professionals should be aware of the oral manifestations to associate to MIS-C which may have high mortality and morbidity rate.
Methods: A total of 54 children with COVID-19 associated MIS-C (n=23) and mild COVID-19 (n=31) were recruited to the study (Age range: 5-15; gender (F/M): 23/31). Sociodemographic variables, medical examinations, oral hygiene habits as well as extra- and intra-oral findings (DMFT/dmft index, OHI scores and oral mucosal changes) were recorded.
Results: MIS-C was associated with cracked lips (all patients with MIS-C) and oral mucosal changes including erythema, white lesion and strawberry tongue and swelling of the gingiva compared to COVID-19 group (frequency of more than one mucosal change: 100% vs 35%) (p<0.001). MIS-C led to 45.8% increase in DMFT/dmft scores higher than 6 (DMFT/dmft (mean±SD): 5.52±3.16 (MIS-C) versus 2.26±1.80 (COVID-19) (p<0.01). Elevated OHI scores was associated with MIS-C (mean±SD: 3.06±1.02 (MIS-C) versus 2.41±0.97 (COVID-19) as well (p<0.05).
Conclusions: Oral manifestations mainly strawberry and erythematous tongue were predominantly associated with MIS-C. Oral/dental symptoms among children with MIS were prevalent. Therefore, dental professionals should be aware of the oral manifestations to associate to MIS-C which may have high mortality and morbidity rate.