Methods: Sealers were mixed according to the manufacturers instructions. Moulds (diameter:20 mm, height:1,5) filled with the mixed root canal sealers were placed in a petri dish in the cabinet at 37 °C and 95% relative humidity for 24 h (n:10). They were weighted nearest 0,001 g. After that they were immersed in 50 ml distilled water for 24 h. After placing the petri dish in a desiccator, the weight change of specimens were recorded.
Results: Kerr Pulp Canal sealer showed the significantly greatest weight loss of all sealers tested (p<0.05). AH26 was the least soluble root canal sealer (p<0.05). The solubility of all sealers were in accordance with ISO (6876/2001) requirements.
Conclusion: Resin based sealers showed less solubility than ZOE based Kerr Pulp sealer.