Methods: A total of 70 extracted human single-rooted teeth were used. All teeth were instrumented using a set of ProTaper rotary instruments. The roots were divided randomly into 6 groups (4 experimental groups of 15 roots each and 2 control groups of 5 roots each). The canal spaces were filled with different combinations of core and sealer using lateral condensation, as follows: group 1, AH Plus + gutta-percha; group 2, AH Plus + Resilon; group 3, Epiphany + Resilon; group 4, Epiphany + gutta-percha. The apical portion of each root was sectioned perpendicular to its long axis to create 10.00 ± 0.05 mm slices. One-week later, apical parts of roots were attached to computerized fluid filtration meter and the apical leakage quantity was determined. Statistical analysis was performed using one-way analysis of variance (ANOVA) and Tukey test, with significance set at P < 0.05.
Results: Group 4 (Epiphany + gutta-percha) had the least amount of microleakage than all the other groups; group 1 (AH Plus + gutta-percha) proved to have second least amount of microleakage among the groups. Group 2 (AH Plus + Resilon) demonstrated the greatest amount of microleakage. There were a significant difference between group 4 (Epiphany + gutta-percha) and group 2 (AH Plus + Resilon) (P < 0.05). It was found that there were no significant differences between group 3 (Epiphany + Resilon) and all the other groups.
Conclusion: The results of this study indicated that the Epiphany sealer and Resilon core combination was not superior to that of the AH Plus sealer and gutta-percha core combination.