Three-year Clinical Evaluation of two all-in-one adhesives in NCCL

Introduction: The aim of this study was to evaluate the clinical performance of S3 Bond (Kuraray Corp, Japan) and G-Bond (GC Corp, Japan) all-in-one bonding agents, over 3 y in non-carious cervical lesions (NCCL). Materials and Methods: Ethics Committee approval was obtained, and 60 restorations were placed in 11 patients aged 45-84 y (mean 60.5 y), using either Clearfil ST resin composite (Kuraray) and S3 Bond or Gradia resin composite (GC) and G-Bond alternately, without phosphoric acid etch on the uncut enamel margins. Patients were recalled at 6 mo, 1 y, 2 y and 3 y, and photographs taken for assessment of colour match and marginal discoloration. Results: One patient was not available at 3 y, providing 54 restorations for evaluation. One restoration of S3/Clearfil ST was lost at 2 years, giving retention rates of 97% for S3 and 100% for G-Bond. At 3 years, six restorations for S3/Clearfil ST showed slight marginal discoloration and one restoration pronounced marginal staining. For G-Bond/Gradia, at 3 years eleven restorations exhibited slight marginal staining and one restoration pronounced marginal staining. Statistical analysis of marginal staining showed no significant difference between the two restoration groups. Discussion: This is one of the few trials that has compared two all-in-one adhesive systems to restore NCCLs over 3-years. G-Bond does not contain HEMA and uses 4-methacryloxyethyl trimellitic acid (4-MET) as the functional monomer to achieve adhesion, compared with 10-MPD as the functional monomer for S3. Both systems achieved similar outcomes. The degree of marginal staining was almost identical for both materials. The outcomes of a 3-year clinical trial using G-Bond reported that pre-etching the uncut enamel with phosphoric acid showed a trend of fewer restorations with marginal staining. Conclusion: Both S3 and G-Bond show excellent clinical performance in NCCL at 3 years. Supported by Kuraray Medical, Japan.