IADR Abstract Archives
MEASUREMENT OF ABRASIVITY OF NEWLY DEVELOPED BIOACTIVE DENTIFRICES: AN IN-VITRO STUDY
Objectives: To determine the relative dentine abrasivity (RDA) of newly developed bioactive dentifrices with three different concentrations of abrasives (nano-sized fluoride containing bioactive glasses (n-BG) and nano-oxides) in comparison with a control dentifrice (Colgate Cavity Protection). Also, the efficacy of these novel dentifrices to occlude dentinal tubules was tested for the treatment of dentine hypersensitivity (DH).
Methods: Total 60 bovine dentine blocks (4mm x 4mm x 2mm) were randomly divided into 6 groups (n=10). The groups corresponded to following brushing treatments: distilled water (negative control), Colgate (positive control RDA=70), n-BG experimental pastes in three different concentrations (A, B and C), and experimental paste D without abrasives. All the specimens were tested for abrasion according to ISO 11609:2010 (10,000 brushing cycles, 150g load, 1.5 years of brushing simulation). Atomic Force Microscopy (AFM), Scanning Electron Microscopy (SEM), Energy Dispersive X-ray (EDX) were used to test roughness average (Ra), surface topography and elemental compositions respectively. The results were analyzed by using SPSS 21, One way ANOVA, Post hoc Tukey and Tamhane’s test. Finally, RDA of experimental dentifrices was determined.
Results: Comparison of Ra differ significantly between all groups with p-value < 0.05 except Colgate (Positive Control) and Experimental paste A, there was no significant difference between these two groups with p-value = 0.764. The RDA values of experimental pastes A, B and C were calculated as 74.04, 84.26 and 116.24 respectively which are well within the acceptable limit set by International standards. All n-BG experimental pastes demonstrated uniform occlusion of almost all the dentinal tubules showing reduction in hypersensitivity.
Conclusions: Acceptable range of RDA and superior occlusion of tubules by novel dentifrices suggest that it may be recommended for treating DH. Further in vivo testing is recommended.
Methods: Total 60 bovine dentine blocks (4mm x 4mm x 2mm) were randomly divided into 6 groups (n=10). The groups corresponded to following brushing treatments: distilled water (negative control), Colgate (positive control RDA=70), n-BG experimental pastes in three different concentrations (A, B and C), and experimental paste D without abrasives. All the specimens were tested for abrasion according to ISO 11609:2010 (10,000 brushing cycles, 150g load, 1.5 years of brushing simulation). Atomic Force Microscopy (AFM), Scanning Electron Microscopy (SEM), Energy Dispersive X-ray (EDX) were used to test roughness average (Ra), surface topography and elemental compositions respectively. The results were analyzed by using SPSS 21, One way ANOVA, Post hoc Tukey and Tamhane’s test. Finally, RDA of experimental dentifrices was determined.
Results: Comparison of Ra differ significantly between all groups with p-value < 0.05 except Colgate (Positive Control) and Experimental paste A, there was no significant difference between these two groups with p-value = 0.764. The RDA values of experimental pastes A, B and C were calculated as 74.04, 84.26 and 116.24 respectively which are well within the acceptable limit set by International standards. All n-BG experimental pastes demonstrated uniform occlusion of almost all the dentinal tubules showing reduction in hypersensitivity.
Conclusions: Acceptable range of RDA and superior occlusion of tubules by novel dentifrices suggest that it may be recommended for treating DH. Further in vivo testing is recommended.