Anaesthetic Complications of Patients Undergoing Surgical Repair of Orofacial Cleft
Objectives: To present the frequency of associated congenital defects, other medical conditions and the peri- operative airway related complications with the anaesthetic management of cleft lip/palate surgeries, conducted at Lagos University Teaching Hospital, Nigeria. Methods: Patients undergoing cleft lip and or palate repair were prospectively studied from January 2015 to December 2019. Demographic data, clinical diagnosis, presence of syndromes and other deformities, type of cleft and cleft surgeries, premedication given, presence of pre-operative medical conditions, peri and post operative complications were recorded. Data were analysed using SPSS software. Data analyzed using median, Interquartile range for numerical data, and absolute/relative frequencies for categorical data. Tests of significance (Chi-square and Fisher’s exact test) were used whenever appropriate. P< 0.05 was considered statistically significant. Results: A total of 150 patients were included, with median age of 15.5 months, and 67 (44.7%) of the patients were less than 12 months old. Majority of the patients were female (56%), and the most common type of cleft was that of lip, alveolus, and palate (36.6%). Sixteen (10.7%) of the patients had associated syndromes, and only two received premedication. Notably, peri-operative complications were observed in 5 (3.3%) of cases, including laryngospasm and difficult intubation. Post-operative complications were rare, with one case of bleeding. Some significant associations were observed, such as premedication with post-operative complications, and the presence of other deformities with peri-operative and post-operative complications (P<0.05). Conclusions: Patients with orofacial clefts and other deformities tend to be predisposed to anaesthetic complications. Peri-operative complications were more frequent with cleft palate repair than with cleft lip and alveolus. Hence, careful pre-operative evaluation and preparation must be ensured to prevent and manage anaesthetic complications in patients undergoing cleft surgeries.