IADR Abstract Archives
Anemia during pregnancy and molar incisor hypomineralization: a systematic review and meta-analysis
Objectives: Anemia is a poorly studied factor in the etiology of molar incisor hypomineralization (MIH). The present systematic review (CRD42021225151) was conducted to assess the association between anemia in the gestational period and molar incisor hypomineralization in children and adolescents.
Methods: Studies in children and teenagers affected by MIH comparing with those not affected by MIH, assessing anemia in the gestational period, were eligible. There were not language or date publication restrictions. Search in eight databases were performed (last update Mar 2021). The risk of bias was assessed by the Newcastle Ottawa Scale modified tool. The association between the anemia and the MIH were assessed by odds ratio (OR) and their corresponding 95% of confidence interval (CI), with a fixed-effect model using the Mantel–Haenszel method.
Results: Three cross-sectional studies from Iraq and Brazil were included in the meta-analysis, comprising 2,877 children from 6 to 12 years old. No data in adolescents were retrived. The results showed a significant association between anemia and MIH (OR 1.69, CI 1.14; 2.51, p = 0.009). The certainty of evidence was considered as moderate, and the risk of bias was low.
Conclusions: Anemia in the gestational period is associated with greater chance for the development of MIH in children.
Methods: Studies in children and teenagers affected by MIH comparing with those not affected by MIH, assessing anemia in the gestational period, were eligible. There were not language or date publication restrictions. Search in eight databases were performed (last update Mar 2021). The risk of bias was assessed by the Newcastle Ottawa Scale modified tool. The association between the anemia and the MIH were assessed by odds ratio (OR) and their corresponding 95% of confidence interval (CI), with a fixed-effect model using the Mantel–Haenszel method.
Results: Three cross-sectional studies from Iraq and Brazil were included in the meta-analysis, comprising 2,877 children from 6 to 12 years old. No data in adolescents were retrived. The results showed a significant association between anemia and MIH (OR 1.69, CI 1.14; 2.51, p = 0.009). The certainty of evidence was considered as moderate, and the risk of bias was low.
Conclusions: Anemia in the gestational period is associated with greater chance for the development of MIH in children.