Gingival hyperplasia in a Mucopolysaccharidosis' patient: a case report

Objectives: This report present a case about treatment of gingival hyperplasia in mucopolysaccharidosis Mucopolysaccharidosis (MPS) is a disorder of storage in which there is excessive accumulation of glycosaminoglycans(GAGs) from lysosomal enzyme defect. Lysosomal accumulation of GAGs eventually results in cell, tissue and organ dysfunction. This patient may manifest mental retardation and physical disorders. The MPS shares many clinical features though in variable degrees. These include chronic and progressive course, multisystem involvements such as organomegaly, dysostosis multiplex of bone and joint. Coarse facial features, claw hand deformity, lumbar kyphosis, decreased muscle tone, hearing and visual disability, obstructive airway and cardiovascular involvement may be seen. Oral manifestations of MPS include enlarged tongue, gingival hyperplasia, multiple impacted teeth and abnormal spacing of teeth. Methods: This clinical report presents a 13-year-old girl with MPS having severe gingival hyperplasia. Gingivectomy was performed under general anesthesia. Patient's oral condition has been controlled periodically. Results: Gingival hyperplasia relapsed but it didn't turned back first condition. Conclusions: The dentist must be aware of oral manifestations present in the MPS. The approach to dental management will require teamwork between the dentist and the patient's physican.