Objectives: We report a case of ameloblastic carcinoma in the mandible. Methods: The patient was a 66 year-old male, who had been aware of the tumor in the right side of the mandible for about six months and underwent partial resection of the mandibular bone. X-ray examination revealed a radiolucent lesion and marked expansion of cortical bone. Results: The resected tumor was solid mass with cystic lesion. Histologically, the tumor was composed of large polygonal cells that exhibited solid, and palisading patterns were easily found. Nests and islands of epithelium within collagenous stroma are composed a peripheral layer of polarized cells enclosing stellate to basaloid cells. And nests had a marked keratinization. Individual cellular features include pleomorphism, frequent mitotic figures, indistinct cell membranes, focal necrosis and loss of cellular cohesion. Immunohistchemically, tumor cells were positive for cytokeratin 13, cytokeratin 14, cytokeratin 19 and AE1/AE3. MIB-1 labelling index was 9.3%. Conclusion: The postoperative histopathological diagnosis was ameloblastic carcinoma in the mandible.
Division: Japanese Division Meeting
Meeting:2008 Japanese Division Meeting (Nagoya City, Japan) Location: Nagoya City, Japan
Year: 2008 Final Presentation ID: Abstract Category|Abstract Category(s):Scientific Groups
Authors
Kubo, Katsutoshi
( Aichigakuin University, Nagoya, N/A, Japan
)
Yoshida, Waka
( Aichigakuin University, Nagoya, N/A, Japan
)
Sugita, Yoshihiko
( Aichigakuin University, Nagoya, N/A, Japan
)
Sato, Emiko
( Aichigakuin University, Nagoya, N/A, Japan
)
Kazaoka, Yoshiaki
( Aichi Medical University Hospital, Nagoya, N/A, Japan
)
Yamada, Shiro
( Aichi Medical University Hospital, Nagoya, N/A, Japan
)
Maeda, Hatsuhiko
( Aichigakuin University, Nagoya, N/A, Japan
)