IADR Abstract Archives

Antimicrobial effects and mechanical properties of acrylic resin containing aPIZAS

Abstract: Objectives: Denture plaque and poor denture hygiene are associated with stomatitis. They may also serve as a reservoir of potential infectious pathogens, and may contribute to oral malodor. The prevention of microbial adhesion to denture surfaces is essential for maintaining good oral hygiene and preventing plaque accumulation. The purpose of present study was to evaluate the antimicrobial effects and mechanical properties of acrylic resin containing aPIZAS. aPIZAS has been shown to suppress the growth of fungi, bacteria, and algae, and is an antibacterial agent that is used in a wide range of fields. It is also chemically stable and safe.Methods: Acrylic resin disk containing 1.5%, 1.0% and 0.5% aPIZAS were used in this study. Acrylic resin disks containing aPIZAS on mechanical strength was evaluated by Water absorption test and three-point bending test. The antimicrobial effects of aPIZAS and acrylic resin disks containing aPIZAS were performed using Streptococcus mutans, Porphyromonas gingivalis and Candida albicans. The deodorizing activity of acrylic resin disks containing aPIZAS immersed in P. gingivalis suspension was also examined.Results: The water absorption, flexural strength and flexural modulus of acrylic resin disks containing aPIZAS were not significantly different from those of acrylic resin disks without aPIZAS. The aPIZAS showed bactericidal activity against P. gingivalis, S. mutans and C. albicans. Bacterial adhesion to the acrylic resin disks containing aPIZAS was significantly lower than those of acrylic resin disks without aPIZAS. Acrylic resin disks containing aPIZAS deodorized methyl mercaptan produced by P. gingivalis.Conclusions: Acrylic resin disks containing 1.0% aPIZAS were confirmed to exert antibacterial effects and deodorant effects. Furthermore, the mechanical properties were similar to disks without aPIZAS. These results suggest that acrylic resin disks containing aPIZAS is very useful as a dental material.
Japanese Division Meeting
2020 Japanese Division Meeting (Virtual)
Virtual, Japan
2020
15
Microbiology/Immunology
  • Inaba, Keitaro  ( Department of Oral Science, Kanagawa Dental University, Yokosuka, Japan )
  • Watanabe, H.  ( Department of Oral Science, Kanagawa Dental University, Yokosuka, Japan )
  • Wada, Y.  ( Department of Oral Science, Kanagawa Dental University, Yokosuka, Japan )
  • Watanabe, S.  ( Department of Oral Science, Kanagawa Dental University, Yokosuka, Japan )
  • Sasaki, H.  ( Department of Oral Science, Kanagawa Dental University, Yokosuka, Japan )
  • Hiramine, H.  ( Department of Highly Advanced Stomatology, Kanagawa Dental University, Yokohama, JAPAN )
  • Sasaki, M.  ( Nissho Chemistry Corporation, Mito, JAPAN )
  • Nihei, T.  ( Department of Oral Science, Kanagawa Dental University, Yokosuka, Japan )
  • Hamada, N.  ( Department of Oral Science, Kanagawa Dental University, Yokosuka, Japan )
    • Poster Session