IADR Abstract Archives
Oxygen Saturation and Pulse Rate Change in Children during Sedation with Oral Midazolam and Nitrous Oxide
Objectives: Various demographic and behavioral parameters may affect the efficacy or safety of sedation of pediatric patients. We evaluated the effect of demographic parameters, behavior parameters, type and duration of treatment on oxygen saturation and pulse rate in children undergoing conscious sedation with oral midazolam and nitrous oxide.
Methods: A retrospective chart review of consecutive pediatric patients, aged 2.5-12.5 years, who had undergone conscious sedation for dental treatment with oral midazolam and nitrous oxide between January 2011 and September 2015. Oral midazolam was administered according to the patients' weight, either at 0.4 mg/kg, 0.5 mg/kg or at a maximum dose of 10 mg. Pulse rate and oxygen saturation were monitored every 15 minutes during treatment
Results: 147 sedation sessions (82 females and 65 males) were included in the study. Sedation was successful in 80% of cases. Children with poor behavior scores had statistically significant different mean saturation levels, albeit within normal range, during the treatment (p<0.012) as well as a clinically significant higher mean pulse rate (p=0.0001), compared to children with good or excellent behavior scores. Treatment duration, the type of dental procedure or the patients' weight were not correlated with the change in oxygen saturation or pulse rate during the treatment.
Conclusions: : Poor behavior of pediatric patients does not affect oxygen saturation, but it increases the pulse rate of children under sedation with midazolam and nitrous-oxide.
Methods: A retrospective chart review of consecutive pediatric patients, aged 2.5-12.5 years, who had undergone conscious sedation for dental treatment with oral midazolam and nitrous oxide between January 2011 and September 2015. Oral midazolam was administered according to the patients' weight, either at 0.4 mg/kg, 0.5 mg/kg or at a maximum dose of 10 mg. Pulse rate and oxygen saturation were monitored every 15 minutes during treatment
Results: 147 sedation sessions (82 females and 65 males) were included in the study. Sedation was successful in 80% of cases. Children with poor behavior scores had statistically significant different mean saturation levels, albeit within normal range, during the treatment (p<0.012) as well as a clinically significant higher mean pulse rate (p=0.0001), compared to children with good or excellent behavior scores. Treatment duration, the type of dental procedure or the patients' weight were not correlated with the change in oxygen saturation or pulse rate during the treatment.
Conclusions: : Poor behavior of pediatric patients does not affect oxygen saturation, but it increases the pulse rate of children under sedation with midazolam and nitrous-oxide.