“Effect of Different Areas on Volumetric Variations of GCF-Myeloperoxidase Levels”

Objectives: Gingival crevicular fluid (GCF) volume is under influence of different factors. There are unique factors those can be effect, GCF Volume and therefore related mode of data presentation. In the related studies are different lacks of these methodological points. The present study mainly aims to analyze on various study models, possible impact of clinical periodontal status, localization of GCF sampling area and clinical periodontal diagnosis on GCF volume and myeloperoxidase (MPO) content. Methods: A total of 51 (23 woman-28 men;mean age 32.06 ± 9.26 years; range 17-60 years) were included in the study. Clinical periodontal status, probing depth, severity of gingival inflammation [Gingival index and gingival bleeding time index] were recorded and GCF samples were obtained from 719 maxillary sites. Subgroups were provided on localization, mesial or distal sites and single rooted-anterior or multi rooted - posterior teeth. MPO activity of GCF was measured using a spectrophotometric MPO assay. MPO levels expressed as total enzyme activity and concentration. Differences between clinical parameters, GCF volume and MPO levels, and correlations were statistically analyzed. Results: Volume and MPO total activity increased if the sites examined given as total sites in a disease related pattern (healthy