Clinical evaluation of "Dentovit" influence on accumulation of dental plaque

Introduction: Dental plaque is the main etiological factor of oral cavity diseases. Brushing of teeth, and use of various chemical substances to prevent its accumulation are not sufficient. Objectives: Clinical assessment of "Dentovit" in prevention of dental plaque accumulation. Methods: 60 persons aged from 18 to 60 of both genders, chosen at random were qualified for the study. High value of Plaque Index was one of the criteria to include a patient in the trial. The subjects did not change their hygienic habits and did not use additional plaque reducing substances. On the baseline, 7, 14, and 28 day PlI (Silness and Löe), GI (Mühleman), and presence of subjective sensations in the mouth of the patients were recorded. Patients were recommended to suck after meals 1 tablet 5 times a day. Preliminary in vitro test of the antibacterial activity of "Dentovit" on chosen aerobic and anaerobic bacteria, isolated from oral cavity, was performed. Results underwent a statistic assessment with chi-square test and relevance level p<0.05. Results: In the case of tested aerobic bacteria no zone of growth restraint was found around the tablet. Around the anaerobic cultures of bacteria (Prevotella melaninogenica and Porphyromonas gingivalis) a zone of growth inhibition was found. After 7 days of the trial, a decrease of the PlI and GI values, feeling of good taste and freshness in the oral cavity, also some dryness in the mouth were found (p<0.001). After 7, 14 and 28 days only the improved value of GI was statistically significant (p<0.001). Conclusion: Dentovit tablets seem to have the beneficiary influence on most patients with a tendency to high scores of PlI in inhibiting plaque accumulation, especially during the first 7 days of use.