Glass-Ionomer Sealants can Prevent Dental Caries but Cannot Prevent Post-Eruptive Breakdown on Molars Affected by Molar Incisor Hypomineralisation (MIH): one-Year Results of a Randomized Clinical Trial
Objectives: To evaluate the preventive effect of glass ionomer cement (GIC) against dental caries and post-eruptive breakdown (PEB) on molars affected by molar incisor hypomineralisation (MIH).
Methods: In this randomized clinical trial, 77 children aged 5 to 9 years with at least one MIH affected molar and without PEB or dentin caries lesions (n=228) were included and randomly allocated into two groups: 1) MIH affected molars that remained non-sealed; 2) MIH affected molars that received GIC-sealants. Dental caries and PEB were clinically evaluated after 6 and 12 months. Associations between dental caries and PEB with independent variables were evaluated using logistic regression analysis (α=5%).
Results: The MIH affected molars allocated to the GIC-sealant group were less likely to develop dental caries compared to those allocated to the non-sealed group (OR=0.23, 95%CI: 0.06-0.95). Conversely, the application of a GIC-sealant was not associated with the prevention of PEB (p = 0.313). Furthermore, MIH affected molars presenting yellow-brown opacities were almost 5-times-more-likely to develop dental caries (p = 0.013) and 5 times-more-likely to develop PEB compared to those presenting white-creamy opacities (p = 0.001).
Conclusions: GIC-sealants can prevent dental caries on MIH affected molars; however, the same protective effect was not observed for PEB.