Effect of calcium hydroxide in combination with betamethasone and ciprofloxacin on planktonic form of Enterococcus focalus
According to the prevalence of Enterococcus faecalis plankton and its identified
complications and the reports validating the influence of betamethasone on inflammation
and reporting a case, (1) the positive effect of calcium hydroxide in combination with
betamethasone against the planktonic form of Enterococcus faecalis, this study was
conducted to compare this drug with standard calcium hydroxide and ciprofloxacin. An in
vitro study was performed on 90 single-channel extracted teeth. After root canal
preparation, including removing the smear layer and maintaining it in TBS and E.faealis,
the samples were randomly selected. The target groups are divided into the following
groups. Group 1, calcium hydroxide oxide powder with betamethasone dye was
combined with 0.1% solid paste, and group 2, calcium hydroxide powder with
ciprofloxacin dye was mixed with 0.3% dough consistency. It should be mentioned that in
the control group, calcium hydroxide powder with saline It was getting pasty. The
microbial evaluation was performed on the first, seventh and tenth days. First, 10
samples were selected from each group at a given time interval. Then, with Gates No. 4
and 5, the canals were opened, and the debris was incubated in 0.1 ml TBS for 24 hours
at 37 ? C. Then the contents of each tube were cultured on agar containing TBS for 48
hours. Subsequently, the number of bacterial colonies was performed using a colony
counter. Finally, the data were analyzed using the Mann-Whitney U test. The findings of
the study revealed that there was no significant difference between CFU in calcium
hydroxide + saline and calcium hydroxide + betamethasone group (p =. / 143). There
was a significant difference between calcium hydroxide + saline and calcium hydroxide +
betamethasone group compared to calcium hydroxide + cyberfloxin group (p = 0.0031
and p = 0.0000). It seems that since the addition of betamethasone to calcium hydroxide
does not reduce its antimicrobial properties, it can be used to reduce the postoperative
inflammation of the patients and the discomfort caused by it. Moreover, cyberfloxin is an
effective intracanal drug for local application (intracanal) due to a significant reduction in
the loading of bacteria.