Methods: In this clinical trial, 28 samples, were sedated randomly, once by the combination of intranasal midazolam with nasal drops of lidocaine hydrochloride 2% without inhalation sedation (A). In the next session, inhalation sedation (N20/02) with intranasal (lidocaine/midazolam) was administered (B). In the second session two protocols were randomly changed. To evaluate the patient's behavior and depth of sedation, Houpt scoring system was used. To compare the redundancy of the items with regard to cross-over design of the study, Wilcoxon-sign Rank test was used.
Results: Of the 28 samples analyzed, group B showed significant difference in the index of general behavior compared to group A only after 15 minutes and at the end of treatment (P<0.05). No significant differences were seen at the time of onset and discharge (P>0.05). Index of movement and crying in group B showed a significant difference compared to group A, only after 15 minutes and at the end of treatment (P<0.05). No significant differences were seen at the time of onset and discharge (P>0.05). Index of drowsiness did not significantly differ between the two groups and at all times (P>0.05).
Conclusions: It is recommended to use inhalation sedation combined with intranasal midazolam to manage the behavior of children undergoing dental treatments.