Methods: 40 patients who had gingivitis were selected. They were assigned to brush their teeth twice daily for three minutes then massage the gums with pastes for one minute and then wash their mouth. The patients were divided into two groups: Arthrodont toothpaste that contains Enoxolon, was given to the test group and Crest toothpaste which does not have Enoxolon, was given to the control group. At the beginning of the study and after 21 days, plaque, gingival, and bleeding indices were measured. The statistical analyses were done by Paird T test, T test and nonparametrical analysis of Wilcoxon and Mann-Whitney.
Results: Statistical analyses showed that in both groups, the three indices had decreased significantly and in comparison between the two groups, the gingival and bleeding indices had significantly decreased in the test group.
Conclusions: The results of this clinical study showed that Enoxolon has anti-inflammatory effect on gingivitis.