Methods: In this study, 40 male albino wistar rats were selected and divided into 5 groups: 1- 20 ug/kg thyroxine was injected intraperitoneally after installation of the orthodontic appliance. 2- 3 I.U thyroxine with cholecalciferol was injected intraperitoneally after installation of the orthodontic appliance. 3- 200 um/kg Thyroxine with calcium gluconate 10% was injected intraperitoneally. 4- thyroxine, cholecalciferol, and calcium gluconate were administered. 5- distilled water was used in control group. In order to calculate the tooth movement, the distance between the upper right first and second molars was measured. The statistical ANOVA test was used in this study.
Results: The average of tooth movement was 0.45±0.13 for group 1, 0.48±0.07 for group 2, 0.37±0.04 for group 3, 0.8±0.20 for group 4, and 0.2±0.066 in control group.
Conclusions: Increased tooth movement was observed for Thyroxine, cholecalciferol, and calcium gluconate group with significant difference (P<0.05).