Methods: In this historical cohort study (cross sectional study) 35 HIV+ patients (case group) and 35 HIV- patients (control group) who referred to the infectious, surgery, or gynecology department of Tehran Imam Khomeini hospital were examined and evaluated. Both groups were matched for age, sex, cigarette smoking, alcohol consumption, OCP using, and pregnancy. The study was done by observation, clinical examination, and interviewing the patients in addition to reviewing their medical files and completing the questionnaire. Oral pigmentation was recorded. The data were analyzed by chi-squared, exact fisher test.
Results: In this study 70 individuals were examined which were equally divided into case and control groups. The prevalence of oral pigmentation was 22.9% (N=8) in the case group and 17.1% (N=6) in the control group. The prevalence of melanin pigmentation in control group was less than healthy individuals but there was no statistically significant difference between the case and control group (P=0.5).
Conclusions: Since there was no significant difference in oral pigmentation in HIV+ and HIV- patients, it can be concluded that in this study, HIV infection does not have any role on oral pigmentation.