Methods: This clinical study has been done on 40 students. Plaque acidity (pH) at distal of first molar were evaluated before and 10 minutes after 10% sucrose consumption. In the next step, CPP-ACP and CPP-ACPF pastes were used as directed on tooth surface. Plaque pH was assessed 30 and 60 minutes, 24, 48, 72 and 96 hours after application, data were recorded and analyzed by Repeated Measure ANOVA statistical method (P<0/05).
Results: Both CPP-ACP and CPP-ACPF increased plaque pH levels, identically for the first 48 hours. The pattern differed after this period.
Conclusions: The effect of CPP-ACP and CPP-ACPF were identical until 48 hours, but CPP-ACPF can be increased the pH until 96 hours.