Methods: a total of 3506 records of archives of Oral Pathology Department of Mashhad Dental School –from 1997 to 2007-were analyzed and two age groups were selected :40 to 60 years old(middle-aged group; MAG) and >60 years old (elderlies; EG).information about sex age and histopthological diagnosis were analyzed between two groups.
Results: 1369 records were eligible. Tumor like lesion were the most frequent diagnostic group with the irritation fibroma as the most frequent single diagnosis in whole study population. Epithelial lesions were more common in EG and leukoplakia and SCC were significantly higher in EG(p<0.05). malignant lesions were significantly higher in EG than MAG(3:1). Oral lichen planus was higher in MAG than EG
Conclusions: emphasize on frequency of biopsied oral lesion in elderlies can give better understanding of treatment needs .